Molecular Genetics and Metabolism Reports is an Open Access journal that publishes molecular and metabolic reports describing investigations that use the tools of biochemistry and molecular biology for studies of normal and diseased states. In addition to original research articles, sequence reports, brief communication reports and letters to the editor are considered.Research Areas include:• Inherited Metabolic Diseases:- Biochemical studies of primary enzyme defects- Molecular genetic analyses of mutations- Pathogenesis of these disorders, including not only primary but also secondary metabolic alterations• Systems Biology:- Functional integration of biochemical network modules- Moonlighting functions of proteins• Intercellular and Intracellular Metabolic Relationships:- Biochemical interactions between cells- Functional roles of and interactions between subcellular compartments and distinct regions within these cellular spaces, termed microcompartments- Metabolic relations between individual enzymes and pathways• Cellular Catalysts:- Protein and nonprotein catalyst in normal and deranged cellular metabolism- Relationships between the structure and function of catalytic molecules- Interaction of these catalysts with other cellular components• Disease Pathogenesis:- Underlying mechanisms of inherited and acquired diseases- Relationships between genotype and phenotype at the biochemical and molecular levels• Treatment:- Drug, protein and dietary interventions- Transplantation and gene therapy- Multicenter clinical trialsAdvances in nanomedicine, nanopediatrics and nanotechnology are also welcome.
Molecular Genetics, Microbiology and Virology addresses theoretical and applied topics in molecular genetics of pro- and eukaryotes, molecular microbiology and molecular virology. The journal focuses on studies of the genetic apparatus of microorganisms, the search for genetic forms of metabolism, genetic mapping of pathogenic causative agents, investigations of the structure and functions of extrachromosomal factors of heredity and migratory genetic elements, and theoretical studies on the mechanisms of genetic regulation. Topics include the molecular and genetic elements of eukaryotic cells, the function of chromosomes and chromatin, the nature of genetic changes in malignant degeneration, hereditary diseases. Also covered are the molecular bases of virology, including viral and cellular genomes integration and viral persistence. The journal's scope of coverage includes the biotechnological production of hormones, components of antiviral vaccines, and diagnostic and therapeutic preparations.
MHR publishes articles on the molecular aspects of human reproductive physiology and pathology, endocrinology, andrology,gonadal function, gametogenesis, fertilization, embryo development, implantation, pregnancy and contraception. Reproductive genetics is also an important part of MHR. Studies on animal models are welcome as long as a clear relevance to human reproduction can be shown. Published papers include peer-reviewed original research reports, short review articles and commentaries. MHR is published on behalf of the European Society of Human Reproduction and Embryology.
Molecular Medicine is the international, peer-reviewed, biomedical journal published by the Feinstein Institute for Medical Research (New York). Molecular Medicine strives to understand normal body functioning and disease pathogenesis at the molecular level, which may allow researchers and physician-scientists to use that knowledge in the design of specific molecular tools for disease diagnosis, treatment, prognosis, and prevention. Manuscripts submitted to the journal should maintain this focus and describe the implications for human disease, at a level approachable by the broad readership of Molecular Medicine. The 2011 Journal Citation Report (JCR), showing impact factors calculated from citations of articles published in 2010 and 2009, lists Molecular Medicine with an impact factor of 3.757. JCR category rankings are as follows: Medicine, Research & Experimental 24/111, Cell Biology 72/180, Biochemistry & Molecular Biology 91/289. Molecular Medicine publishes work in the format of original research articles, review articles, editorials, commentaries and letters to the editor covering emerging concepts in the interdisciplinary field of molecular medicine.Molecular Medicine places high priority on rapid publication. All content is published free online, ahead of print, within an average of 8 days after acceptance on our Web site www.molmed.org. Following acceptance, papers are posted rapidly to PubMed, with an e-publication ahead of print citation. Molecular Medicine is an open access journal and does not embargo content.
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Molecular Oncology highlights new discoveries, approaches, as well as technical developments, in basic, clinical and discovery-driven translational research. Topics include:• Key biological processes such as cell cycle; DNA repair; apoptosis; invasion and metastasis; angiogenesis and lymphangiogenesis; cell signalling and interactive networks; immune response.• Emerging technologies (genomics, proteomics, functional genomics, metabolomics, tissue arrays, imaging), and model systems.•Biomarkers: diagnosis, prognosis, stratification and efficacy.• Cancer genetics, epigenetics, and genomic instability.• Minimal residual disease, pre-malignant lesions.• Cancer micro-environment.• Molecular pathology.• Tumour immunology.• Translational research.• Cancer therapy (target discovery, drug design, immunotherapy, combination therapies, resistance, and individualised treatment).• Chemotherapy, radiotherapy and surgery.• Clinical pharmacology.• Clinical trials, integration of basic science into cancer clinical trials.• Epidemiology and prevention.• Infrastructures (biobanks, databases, genomic resources).A main feature of the Journal is to provide an international forum for debating cancer issues, and for integrating the input of all the stakeholders.Coverage: Reviews, original articles, technical notes, editorials, news & views (commentary, science policy issues, ethical and legal issues, patient organisations, industry needs and alliances, regulatory issues, news items), letters to the editor, conference announcements, advertisements.Submitting Authors:Manuscripts can be submitted to Molecular Oncology at:http://ees.elsevier.com/molonc/
Molecular Phylogenetics and Evolution is dedicated to bringing Darwin's dream within grasp - to "have fairly true genealogical trees of each great kingdom of Nature." The journal provides a forum for molecular studies that advance our understanding of phylogeny and evolution, further the development of phylogenetically more accurate taxonomic classifications, and ultimately bring a unified classification for all the ramifying lines of life. Phylogeographic studies will be considered for publication if they offer EXCEPTIONAL theoretical or empirical advances.The journal encourages articles that are multidisciplinary, especially in areas, such as bioinformatics, computational biology, molecular biology, and organismic biology, that are of interest to the community of systematic and evolutionary biologists. In addition, presentations of new findings on or insights into evolutionary processes and mechanisms as expressed at the molecular level are welcome, as are those that deal with the methodology of reconstructing evolutionary history from molecular data (such as descriptions of new or more powerful computer algorithms for constructing phylogenetic trees from orthologous nucleotide or aminoacid sequences). A deeper understanding of the mechanisms and processes of molecular evolution should lead to more accurate models of molecular evolution, which in turn should facilitate the development of better algorithms for reconstructing evolutionary history from sequence data.Papers based on few taxa, single molecular markers, or that use codon-based methods to test for positive Darwinian selection, but in the absence of experimental evidence that allegedly selected amino acid changes cause an adaptive phenotypic effect, will not be accepted.Benefits to authorsWe also provide many author benefits, such as free PDFs, a liberal copyright policy, special discounts on Elsevier publications and much more. Please click here for more information on our author services .Please see our Guide for Authors for information on article submission. If you require any further information or help, please visit our support pages: http://support.elsevier.com
Molecular Reproduction and Development takes an integrated, systems-biology approach to understand the dynamic continuum of cellular, reproductive, and developmental processes. This journal fosters dialogue among diverse disciplines through primary research communications and educational forums, with the philosophy that fundamental findings within the life sciences result from a convergence of disciplines. Increasingly, readers of the Journal need to be informed of diverse, yet integrated, topics impinging on their areas of interest. This requires an expansion in thinking towards non-traditional, interdisciplinary experimental design and data analysis. For example, biologists need to know how nanodevices might be used, while bioengineers need to know how post-translational protein modifications affect developmental mechanisms. The Journal will provide a means for readers to integrate divergent scientific disciplines into their current and future research. Readers will turn to Molecular Reproduction and Development not only to learn the latest in research progress, but to become educated in frontier topics of the field of reproductive and developmental biology; students in particular will turn to the Journal to learn about current progress in the diversifying approaches that will become the foundation for the next generation of research.
Molecular Syndromology publishes high-quality research articles, short reports, and reviews on common and rare genetic syndromes, aiming to increase clinical understanding through molecular insights. Topics of particular interest are the molecular basis of genetic syndromes, genotype-phenotype correlation, natural history, strategies in disease management and novel therapeutic approaches based on molecular findings. Research on model systems is also welcome, especially when it is obviously relevant to human genetics. With high-quality reviews on current topics, the journal aims to facilitate translation of research findings to a clinical setting while also stimulating further research on clinically relevant questions. The journal targets not only medical geneticists and basic biomedical researchers, but also clinicians dealing with genetic syndromes. With 4 associate editors from 3 continents and a broad international editorial board, the journal welcomes submissions covering the lates
Molecular Therapy is the leading journal for research in the areas of gene transfer, vector development and design, stem cell manipulation, development of gene-, peptide- and protein-, oligonucleotide- and cell-based therapeutics to correct genetic and acquired diseases, vaccine development, pre-clinical target validation, safety/efficacy studies, and clinical trials. Available in print and online, Molecular Therapy is dedicated to promoting the sciences in genetics, medicine and biotechnology. Publishing important peer-reviewed research and cutting-edge reviews and commentaries, the journal continues to attract the best material in the field. Molecular Therapy's 2009 impact factor is 6.239*.
methods, technology development, molecular therapy, gene therapy
CSIRO PUBLISHING publishes journals presenting the latest research by leading Australian and overseas scientists and covering a broad range of subjects.Browse one of our journals from the list below. Each journal home page provides specific information for potential authors and subscribers.
Mutagenesis is an international multi-disciplinary journal designed to bring together research aimed at the identification, characterization and elucidation of the mechanisms of action of physical, chemical and biological agents capable of producing genetic change in living organisms and the study of the consequences of such changes.
Mutation Research: Fundamental and Molecular Mechanisms of Mutagenesis broadly encompasses all aspects of research that address the detection of mutations, the mechanisms by which mutations in genes and chromosomes arise, and the modulation of mutagenesis by mutation avoidance pathways such as DNA repair, cell cycle control and apoptosis. It includes the role of genetic variation in the genesis and manifestation of mutations, ranging from the variable manner in which xenobiotics are metabolized to variations in the capacity of cells to replicate and repair damaged DNA. It also includes the contributions of these mechanisms, when perturbed, to animal disease models and to human disease, with particular emphasis on carcinogenic mechanisms. The Journal will publish articles on the genesis of aneuploidy and isodisomy, including the roles played by recombination, cell cycle checkpoints, spindle microtubules, centrosomes and kinetocore proteins, and agents that might disrupt them. Submission of appropriate epidemiological studies as well as consequences, including methods for high throughput SNP detection, whole genome and exonic sequencing, DNA microarrays, RNAseq approaches and proteomics are welcome. Submission of preliminary epidemiological studies that associate SNPs with a phenotype but provide no mechanistic insight is discouraged. The broader scope of the journal is a reflection of the rapid advances in the field of mutation research and the recognition that understanding of the mutagenic process requires full knowledge of the cellular response to DNA damage including DNA repair, cell cycle checkpoint arrest and apoptosis.Benefits to authorsWe also provide many author benefits, such as free PDFs, a liberal copyright policy, special discounts on Elsevier publications and much more. Please click here for more information on our author services .Please see our Guide for Authors for information on article submission. If you require any further information or help, please visit our support pages: http://support.elsevier.com
Mutation Research - Genetic Toxicology and Environmental Mutagenesis publishes papers advancing knowledge in the field of genetic toxicology. Papers are welcomed in the following areas:New developments in genotoxicity testing of chemical agents (e.g. improvements in methodology of assay systems and interpretation of results).Alternatives to and refinement of the use of animals in genotoxicity testing.Nano-genotoxicology, the study of genotoxicity hazards and risks related to novel man-made nanomaterials.Studies of epigenetic changes in relation to genotoxic effects.The use of structure-activity relationships in predicting genotoxic effects.The isolation and chemical characterization of novel environmental mutagens.The measurement of genotoxic effects in human populations, when accompanied by quantitative measurements of environmental or occupational exposures.The application of novel technologies for assessing the hazard and risks associated with genotoxic substances (e.g. OMICS or other high-throughput approaches to genotoxicity testing).Mutation Research - Genetic Toxicology and Environmental Mutagenesis is now accepting submissions for a new section of the journal that will be dedicated to the discussion of current issues relating to design, interpretation and strategic use of genotoxicity tests (Current Topics in Genotoxicity Testing). This section is envisaged to include discussions relating to the development of new international testing guidelines, but also to wider topics in the field. The evaluation of contrasting or opposing viewpoints is welcomed as long as the presentation is in accordance with the journal's aims, scope, and policies.Benefits to authorsWe also provide many author benefits, such as free PDFs, a liberal copyright policy, special discounts on Elsevier publications and much more. Please click here for more information on our author services .Please see our Guide for Authors for information on article submission. If you require any further information or help, please visit our support pages: http://support.elsevier.com
The subject areas of Reviews in Mutation Research encompass the entire spectrum of the science of mutation research and its applications, with particular emphasis on the relationship between mutation and disease. Thus this section will cover advances in human genome research (including evolving technologies for mutation detection andfunctional genomics) with applications in clinical genetics, gene therapy and health risk assessment for environmental agents of concern.Genetic toxicology and environmental mutagenesis (including the factors that modulate the genetic activity of environmental agents) will continue to be prominent topics in this section. In addition to full-length reviews, mini-reviews on specific topical themes will be published.Benefits to authorsWe also provide many author benefits, such as free PDFs, a liberal copyright policy, special discounts on Elsevier publications and much more. Please click here for more information on our author services.Please see our Guide for Authors for information on article submission. If you require any further information or help, please visit our support pages: http://support.elsevier.com
MYCOLOGIA publishes papers on all aspects of the fungi, including lichens. Subjects appropriate to the journal are physiology and biochemistry, ecology, pathology, development and morphology, systematics, cell biology and ultrastructure, genetics, molecular biology, evolution, applied aspects, and new techniques. Publication in MYCOLOGIA is for both members and nonmembers of the Mycological Society of America. Papers appropriate for the journal are:(i) regular articles reporting original research(ii) notes or brief articles reporting research or new techniques(iii) invited papers(iv) reviews, and minireviews.
Mycorrhiza is an international journal devoted to research into mycorrhizas - the widest symbioses in nature, involving plants and a range of soil fungi world-wide. The journal covers research into mycorrhizas, including molecular biology of the plants and fungi, fungal systematics, development and structure of mycorrhizas, and effects on plant physiology, productivity, reproduction and disease resistance. Coverage extends to interactions between mycorrhizal fungi and other soil organisms, and effects of mycorrhizas on plant biodiversity and ecosystem structure. Mycorrhiza presents original papers, short notes and review articles, along with commentaries and news items. It offers a platform for new concepts and discussions, and serves as the basis for a forum of mycorrhizologists from around the world. Managing Editors: Vivienne Gianinazzi-Pearson, Dijon, France, and Randy Molina, Gresham, Oregon, USA Mycorrhiza is the official organ of the International Mycorrhiza Society.
Nature Genetics publishes the very highest quality research in genetics. It encompasses genetic and functional genomic studies on human traits and on other model organisms, including mouse, fly, nematode and yeast. Current emphasis is on the genetic basis for common and complex diseases and on the functional mechanism, architecture and evolution of gene networks, studied by experimental perturbation.Integrative genetic topics comprise, but are not limited to:* Genes in the pathology of human disease* Molecular analysis of simple and complex genetic traits* Cancer genetics* Epigenetics* Gene therapy* Developmental genetics* Regulation of gene expression* Strategies and technologies for extracting function from genomic data* Pharmacological genomics* Genome evolution.